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I am able to disable Seconardy O2 sensor. Does the secondardy O2 sensor needs to be plugin after it has been disabled.

There are 6 items under OBD2 Monitor that are in grey. Are those currently not supported? Will it be supported in the future?

KTuner wrote:Secondary O2 is always a standard option. EGR can be added if the system has it. EVAP is not generally a standard disable.

You can unplug the secondary if you disable it. If it's not available then it's not supported.